Moringa Oleifera and Memory Loss. Please read it

Moringa Oleifera and Memory Loss

If you know of someone who is experiencing memory loss, Moringa Oleifera could provide some benefits.
Moringa, a small tree found in Asian and African countries, has recently been found to protect cognitive skills and memory in rats. Moringa has antioxidants that help reduce oxidative stress in Alzheimer's patients (AD). The leaves also provide protection under reduced oxygen levels by showing increases in the brain monoamines, dopamine, norepinephrine and serotonin. Reductions in these three monoamines are associated with memory loss. Let's look at this more closely.
Cholinergic neurons in Alzheimer's Disease are reduced in both humans and animals. This loss is reported in AD patients with dopamine, norepinephrine and/or serotonin depletion. For example, depression, dementia and diminished alertness and concentration are related to norepinephrine deficits. Response selection and habit learning are related to dopamine deficits. In addition, anxiety in AD is related to serotonin (5-hydroxytryptamine or 5-HT) neurons.
In an experiment by Dr. Ganguly's group, rats were given an infusion of colchicine that causes monoamine deficits associated with AD. Colchicine destroys the microtubule integrity of neurons that leads to cell degeneration. The colchicine impaired the rats' Radical Arm Maze (RAM) training. There was also a loss of norepinephrine and dopamine in the cerebral cortex, hippocampus and caudate nucleus and a loss of serotonin in the cerebral cortex. After the cholchicine, the rat EEG studies showed a decrease in the beta and alpha waves. There was instead, an increase in the rat biphasic spike wave pattern. Treatment with the Moringa oleifera leaf extract (250 mg/kg) for fourteen days markedly increased the correct choices in the RAM training. The EEG studies also showed an increase in beta waves and a decrease in the spike wave discharges. Treatment with Moringa oleifera was associated with an increase in monoamine levels that approached the original control levels. The Moringa group of rats showed reduced levels of damaged neurons, compared to the rats that just got the cholchicine. The authors conclude that Moringa oleifera may provide protection against Alzheimer's Disease by increasing the brain monoamines (dopamine, norepinephrine and serotonin) and electrical activity back towards control levels.
Moringa Max is from the best Moringa supply available, in Southern India. Our product has the highest quality and purity of ingredients for the Moringa oleifera leaf powder.

Ganguly R, Guha D. Alteration of brain monoamines & EEG wave pattern in rat model of Alzheimer's disease & protection by Moringa oleifera. Indian J Med Res 2008; 128(6): 744-51.



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